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Prohibitin-induced, obesity-associated insulin resistance and accompanying low-grade inflammation causes NASH and HCC
Obesity increases the risk for nonalcoholic steatohepatitis (NASH) and hepatocarcinogenesis. However, the underlying mechanisms involved in the disease process remain unclear. Recently, we have developed a transgenic obese mouse model (Mito-Ob) by prohibitin mediated mitochondrial remodeling in adip...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4804274/ https://ncbi.nlm.nih.gov/pubmed/27005704 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23608 |
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