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Evolution of the vertebrate insulin receptor substrate (Irs) gene family
BACKGROUND: Insulin receptor substrate (Irs) proteins are essential for insulin signaling as they allow downstream effectors to dock with, and be activated by, the insulin receptor. A family of four Irs proteins have been identified in mice, however the gene for one of these, IRS3, has been pseudoge...
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| Udgivet i: | BMC Evol Biol |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5482937/ https://ncbi.nlm.nih.gov/pubmed/28645244 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12862-017-0994-z |
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