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Promoter deletion and loss of retinoblastoma gene expression in human prostate carcinoma.

Mutational inactivation of the retinoblastoma gene (RB) is found in all retinoblastomas and in a subset of other human neoplasms, including sarcomas of bone or soft tissue and carcinomas of lung or breast. Exogenous copies of wild-type RB have been shown to suppress the tumorigenicity of several typ...

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Autors principals: Bookstein, R, Rio, P, Madreperla, S A, Hong, F, Allred, C, Grizzle, W E, Lee, W H
Format: Artigo
Idioma:Inglês
Publicat: 1990
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC54828/
https://ncbi.nlm.nih.gov/pubmed/2217208
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