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IFNγ-producing CD4(+) T lymphocytes: the double-edged swords in tuberculosis
IFNγ-producing CD4(+) T cells (IFNγ(+)CD4(+) T cells) are the key orchestrators of protective immunity against Mycobacterium tuberculosis (Mtb). Primarily, these cells act by enabling Mtb-infected macrophages to enforce phagosome-lysosome fusion, produce reactive nitrogen intermediates (RNIs), and a...
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| Publié dans: | Clin Transl Med |
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| Auteur principal: | |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Springer Berlin Heidelberg
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5482791/ https://ncbi.nlm.nih.gov/pubmed/28646367 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40169-017-0151-8 |
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