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IFNγ-producing CD4(+) T lymphocytes: the double-edged swords in tuberculosis

IFNγ-producing CD4(+) T cells (IFNγ(+)CD4(+) T cells) are the key orchestrators of protective immunity against Mycobacterium tuberculosis (Mtb). Primarily, these cells act by enabling Mtb-infected macrophages to enforce phagosome-lysosome fusion, produce reactive nitrogen intermediates (RNIs), and a...

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Detaylı Bibliyografya
Yayımlandı:Clin Transl Med
Yazar: Kumar, Pawan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer Berlin Heidelberg 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482791/
https://ncbi.nlm.nih.gov/pubmed/28646367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40169-017-0151-8
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