Imaging of pH in vivo using hyperpolarized (13)C-labelled zymonic acid

Natural pH regulatory mechanisms can be overruled during several pathologies such as cancer, inflammation and ischaemia, leading to local pH changes in the human body. Here we demonstrate that (13)C-labelled zymonic acid (ZA) can be used as hyperpolarized magnetic resonance pH imaging sensor. ZA is...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Düwel, Stephan, Hundshammer, Christian, Gersch, Malte, Feuerecker, Benedikt, Steiger, Katja, Buck, Achim, Walch, Axel, Haase, Axel, Glaser, Steffen J., Schwaiger, Markus, Schilling, Franz
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482723/
https://ncbi.nlm.nih.gov/pubmed/28492229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15126
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