Low numbers of pre-leukemic fusion genes are frequently present in umbilical cord blood without affecting DNA damage response

Despite widely accepted notion that many childhood leukemias are likely developed from hematopoietic stem/progenitor cells (HSPC) with pre-leukemic fusion genes (PFG) formed in embryonic/fetal development, the data on PFG incidence in newborns are contradictive. To provide a better understanding of...

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Publicado en:Oncotarget
Autores principales: Kosik, Pavol, Skorvaga, Milan, Durdik, Matus, Jakl, Lukas, Nikitina, Ekaterina, Markova, Eva, Kozics, Katarina, Horvathova, Eva, Belyaev, Igor
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482620/
https://ncbi.nlm.nih.gov/pubmed/28415763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16211
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