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Division of labor: ER-resident J-proteins match substrates to fates based on specific binding sequences

In this issue, Behkne et al. describe a novel cell-based peptide binding assay and use it to analyze the binding specificities of the endoplasmic reticulum Hsp70 chaperone and its co-chaperones and to probe their different roles in protein quality control.

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Hebert, Daniel N., Clerico, Eugenia M., Gierasch, Lila M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482365/
https://ncbi.nlm.nih.gov/pubmed/27588598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.08.017
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