Characterization of constitutive and acid-induced outwardly rectifying chloride currents in immortalized mouse distal tubular cells

Thiazides block Na(+) reabsorption while enhancing Ca(2+) reabsorption in the kidney. As previously demonstrated in immortalized mouse distal convoluted tubule (MDCT) cells, chlorothiazide application induced a robust plasma membrane hyperpolarization, which increased Ca(2+) uptake. This essential t...

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Udgivet i:Biochim Biophys Acta
Main Authors: Valinsky, William C., Touyz, Rhian M., Shrier, Alvin
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier Pub. Co 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482324/
https://ncbi.nlm.nih.gov/pubmed/28483640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2017.05.004
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