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Aldosterone, SGK1, and ion channels in the kidney
Hyperaldosteronism, a common cause of hypertension, is strongly connected to Na(+), K(+), and Mg(2+) dysregulation. Owing to its steroidal structure, aldosterone is an active transcriptional modifier when bound to the mineralocorticoid receptor (MR) in cells expressing the enzyme 11β-hydroxysteroid...
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| 出版年: | Clin Sci (Lond) |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Portland Press Ltd.
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5817097/ https://ncbi.nlm.nih.gov/pubmed/29352074 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/CS20171525 |
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