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A novel missense mutation in the ALPL gene causes dysfunction of the protein

Hypophosphatasia (HP) is a rare genetic disease caused by mutation in the alkaline phosphatase, liver/bone/kidney (ALPL) gene with highly variable clinical manifestations. Efforts have been made to collect cases with novel mutations and to examine how a missense mutation affects ALPL protein functio...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: Chen, Bin, Li, Lili, Ren, Weitong, Yi, Long, Wang, Yaping, Yan, Fuhua
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482188/
https://ncbi.nlm.nih.gov/pubmed/28586049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2017.6668
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