Hypoglycemic Effect of Combined Ghrelin and Glucagon Receptor Blockade

Glucagon receptor (GcgR) blockade has been proposed as an alternative to insulin monotherapy for treating type 1 diabetes since deletion or inhibition of GcgRs corrects hyperglycemia in models of diabetes. The factors regulating glycemia in a setting devoid of insulin and glucagon function remain un...

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Publicat a:Diabetes
Autors principals: Mani, Bharath K., Uchida, Aki, Lee, Young, Osborne-Lawrence, Sherri, Charron, Maureen J., Unger, Roger H., Berglund, Eric D., Zigman, Jeffrey M.
Format: Artigo
Idioma:Inglês
Publicat: American Diabetes Association 2017
Matèries:
Metabolism
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5482080/
https://ncbi.nlm.nih.gov/pubmed/28487437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db16-1303
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