Ca(2+)-Permeable AMPARs Mediate Glutamatergic Transmission and Excitotoxic Damage at the Hair Cell Ribbon Synapse

We report functional and structural evidence for GluA2-lacking Ca(2+)-permeable AMPARs (CP-AMPARs) at the mature hair cell ribbon synapse. By using the methodological advantages of three species (of either sex), we demonstrate that CP-AMPARs are present at the hair cell synapse in an evolutionarily...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Sebe, Joy Y., Cho, Soyoun, Sheets, Lavinia, Rutherford, Mark A., von Gersdorff, Henrique, Raible, David W.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2017
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5481947/
https://ncbi.nlm.nih.gov/pubmed/28539424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3644-16.2017
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