Establishment of an orthotopic patient-derived xenograft mouse model using uveal melanoma hepatic metastasis

BACKGROUND: Metastatic uveal melanoma is a highly fatal disease; most patients die from their hepatic metastasis within 1 year. A major drawback in the development of new treatments for metastatic uveal melanoma is the difficulty in obtaining appropriate cell lines and the lack of appropriate animal...

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Dettagli Bibliografici
Pubblicato in:J Transl Med
Autori principali: Kageyama, Ken, Ohara, Masahiro, Saito, Kengo, Ozaki, Shinji, Terai, Mizue, Mastrangelo, Michael J., Fortina, Paolo, Aplin, Andrew E., Sato, Takami
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
Soggetti:
Methodology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5481921/
https://ncbi.nlm.nih.gov/pubmed/28645290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-017-1247-z
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