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Antagonistic regulation of cell-cycle and differentiation gene programs in neonatal cardiomyocytes by homologous MEF2 transcription factors

Cardiomyocytes acquire their primary specialized function (contraction) before exiting the cell cycle. In this regard, proliferation and differentiation must be precisely coordinated for proper cardiac morphogenesis. Here, we have investigated the complex transcriptional mechanisms employed by cardi...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Desjardins, Cody A., Naya, Francisco J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5481567/
https://ncbi.nlm.nih.gov/pubmed/28473466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.776153
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