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Antagonistic regulation of cell-cycle and differentiation gene programs in neonatal cardiomyocytes by homologous MEF2 transcription factors

Cardiomyocytes acquire their primary specialized function (contraction) before exiting the cell cycle. In this regard, proliferation and differentiation must be precisely coordinated for proper cardiac morphogenesis. Here, we have investigated the complex transcriptional mechanisms employed by cardi...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Desjardins, Cody A., Naya, Francisco J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5481567/
https://ncbi.nlm.nih.gov/pubmed/28473466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.776153
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