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The crystal structure of mammalian inositol 1,3,4,5,6-pentakisphosphate 2-kinase reveals a new zinc-binding site and key features for protein function
Inositol 1,3,4,5,6-pentakisphosphate 2-kinases (IP(5) 2-Ks) are part of a family of enzymes in charge of synthesizing inositol hexakisphosphate (IP(6)) in eukaryotic cells. This protein and its product IP(6) present many roles in cells, participating in mRNA export, embryonic development, and apopto...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5481561/ https://ncbi.nlm.nih.gov/pubmed/28450399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.780395 |
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