Hypoxia mediates mitochondrial biogenesis in hepatocellular carcinoma to promote tumor growth via HMGB1 and TLR9 interaction

The ability of cancer cells to survive and grow under hypoxic conditions has been known for decades, but the mechanisms remain poorly understood. Under certain conditions, cancer cells undergo changes in their bioenergetic profile to favor mitochondrial respiration by activating the peroxisome proli...

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Bibliografische gegevens
Gepubliceerd in:Hepatology
Hoofdauteurs: Tohme, Samer, Yazdani, Hamza O, Liu, Yao, Loughran, Patricia, van der Windt, Dirk J, Huang, Hai, Simmons, Richard L, Shiva, Sruti, Tai, Sheng, Tsung, Allan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5481489/
https://ncbi.nlm.nih.gov/pubmed/28370295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.29184
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