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Structural basis for biologically relevant mechanical stiffening of a virus capsid by cavity-creating or spacefilling mutations

Recent studies reveal that the mechanical properties of virus particles may have been shaped by evolution to facilitate virus survival. Manipulation of the mechanical behavior of virus capsids is leading to a better understanding of viral infection, and to the development of virus-based nanoparticle...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Guerra, Pablo, Valbuena, Alejandro, Querol-Audí, Jordi, Silva, Cristina, Castellanos, Milagros, Rodríguez-Huete, Alicia, Garriga, Damià, Mateu, Mauricio G., Verdaguer, Nuria
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5481337/
https://ncbi.nlm.nih.gov/pubmed/28642465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04345-w
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