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Structural basis for biologically relevant mechanical stiffening of a virus capsid by cavity-creating or spacefilling mutations

Recent studies reveal that the mechanical properties of virus particles may have been shaped by evolution to facilitate virus survival. Manipulation of the mechanical behavior of virus capsids is leading to a better understanding of viral infection, and to the development of virus-based nanoparticle...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Guerra, Pablo, Valbuena, Alejandro, Querol-Audí, Jordi, Silva, Cristina, Castellanos, Milagros, Rodríguez-Huete, Alicia, Garriga, Damià, Mateu, Mauricio G., Verdaguer, Nuria
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5481337/
https://ncbi.nlm.nih.gov/pubmed/28642465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04345-w
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