Whole Exome Sequencing to Identify Genetic Variants Associated with Raised Atherosclerotic Lesions in Young Persons

We investigated the influence of genetic variants on atherosclerosis using whole exome sequencing in cases and controls from the autopsy study “Pathobiological Determinants of Atherosclerosis in Youth (PDAY)”. We identified a PDAY case group with the highest total amounts of raised lesions (n = 359)...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hixson, James E., Jun, Goo, Shimmin, Lawrence C., Wang, Yizhi, Yu, Guoqiang, Mao, Chunhong, Warren, Andrew S., Howard, Timothy D., Heide, Richard S. Vander, Van Eyk, Jennifer, Wang, Yue, Herrington, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5481334/
https://ncbi.nlm.nih.gov/pubmed/28642624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04433-x
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