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MeCP2 regulates Tet1-catalyzed demethylation, CTCF binding, and learning-dependent alternative splicing of the BDNF gene in Turtle

MECP2 mutations underlying Rett syndrome cause widespread misregulation of gene expression. Functions for MeCP2 other than transcriptional are not well understood. In an ex vivo brain preparation from the pond turtle Trachemys scripta elegans, an intraexonic splicing event in the brain-derived neuro...

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Библиографические подробности
Опубликовано в: :eLife
Главные авторы: Zheng, Zhaoqing, Ambigapathy, Ganesh, Keifer, Joyce
Формат: Artigo
Язык:Inglês
Опубликовано: eLife Sciences Publications, Ltd 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5481183/
https://ncbi.nlm.nih.gov/pubmed/28594324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.25384
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