Alcohol-associated intestinal dysbiosis impairs pulmonary host defense against Klebsiella pneumoniae

Chronic alcohol consumption perturbs the normal intestinal microbial communities (dysbiosis). To investigate the relationship between alcohol-mediated dysbiosis and pulmonary host defense we developed a fecal adoptive transfer model, which allows us to investigate the impact of alcohol-induced gut d...

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Udgivet i:PLoS Pathog
Main Authors: Samuelson, Derrick R., Shellito, Judd E., Maffei, Vincent J., Tague, Eric D., Campagna, Shawn R., Blanchard, Eugene E., Luo, Meng, Taylor, Christopher M., Ronis, Martin J. J., Molina, Patricia E., Welsh, David A.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5481032/
https://ncbi.nlm.nih.gov/pubmed/28604843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006426
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