Reliability and performance of commercial RNA and DNA extraction kits for FFPE tissue cores

Cancer biomarker studies often require nucleic acid extraction from limited amounts of formalin-fixed, paraffin-embedded (FFPE) tissues, such as histologic sections or needle cores. A major challenge is low quantity and quality of extracted nucleic acids, which can limit our ability to perform genet...

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Bibliographic Details
Published in:PLoS One
Main Authors: Patel, Palak G., Selvarajah, Shamini, Guérard, Karl-Philippe, Bartlett, John M. S., Lapointe, Jacques, Berman, David M., Okello, John B. A., Park, Paul C.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5480995/
https://ncbi.nlm.nih.gov/pubmed/28640876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0179732
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