Inhibition of NF-κB improves the stress resistance and myogenic differentiation of MDSPCs isolated from naturally aged mice

A decline in the regenerative capacity of adult stem cells with aging is well documented. As a result of this decline, the efficacy of autologous stem cell therapies is likely to decline with increasing donor age. In these cases, strategies to restore the function of aged stem cells would have clini...

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Vydáno v:PLoS One
Hlavní autoři: Proto, Jonathan D., Lu, Aiping, Dorronsoro, Akaitz, Scibetta, Alex, Robbins, Paul D., Niedernhofer, Laura J., Huard, Johnny
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5480862/
https://ncbi.nlm.nih.gov/pubmed/28640861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0179270
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