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Inhibition of NF-κB improves the stress resistance and myogenic differentiation of MDSPCs isolated from naturally aged mice

A decline in the regenerative capacity of adult stem cells with aging is well documented. As a result of this decline, the efficacy of autologous stem cell therapies is likely to decline with increasing donor age. In these cases, strategies to restore the function of aged stem cells would have clini...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Proto, Jonathan D., Lu, Aiping, Dorronsoro, Akaitz, Scibetta, Alex, Robbins, Paul D., Niedernhofer, Laura J., Huard, Johnny
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5480862/
https://ncbi.nlm.nih.gov/pubmed/28640861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0179270
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