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Autofluorescence imaging captures heterogeneous drug response differences between 2D and 3D breast cancer cultures

Two-photon microscopy of cellular autofluorescence intensity and lifetime (optical metabolic imaging, or OMI) is a promising tool for preclinical drug development. OMI, which exploits the endogenous fluorescence from the metabolic coenzymes NAD(P)H and FAD, is sensitive to changes in cell metabolism...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Biomed Opt Express
Päätekijät: Cannon, T. M., Shah, A. T., Skala, M. C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Optical Society of America 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5480588/
https://ncbi.nlm.nih.gov/pubmed/28663873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1364/BOE.8.001911
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