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Autofluorescence imaging captures heterogeneous drug response differences between 2D and 3D breast cancer cultures
Two-photon microscopy of cellular autofluorescence intensity and lifetime (optical metabolic imaging, or OMI) is a promising tool for preclinical drug development. OMI, which exploits the endogenous fluorescence from the metabolic coenzymes NAD(P)H and FAD, is sensitive to changes in cell metabolism...
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| Publicado no: | Biomed Opt Express |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Optical Society of America
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5480588/ https://ncbi.nlm.nih.gov/pubmed/28663873 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1364/BOE.8.001911 |
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