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Regioselective (thio)carbamoylation of 2,7-di-tert-butylpyrene at the 1-position with iso(thio)cyanates

It has been found that 2,7-di-tert-butylpyrene reacts with aliphatic iso(thio)cyanates in the presence of trifluoromethanesulfonic acid to exclusively afford the corresponding 1-substituted (thio)amides in high yields. For aromatic iso(thio)cyanates the reaction is less regioselective, although subs...

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Bibliographic Details
Published in:Beilstein J Org Chem
Main Authors: Wrona-Piotrowicz, Anna, Witalewska, Marzena, Zakrzewski, Janusz, Makal, Anna
Format: Artigo
Language:Inglês
Published: Beilstein-Institut 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5480332/
https://ncbi.nlm.nih.gov/pubmed/28684982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.13.102
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