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Involvement of Human MCM8 in Prereplication Complex Assembly by Recruiting hcdc6 to Chromatin

The MCM2-MCM7 complex is an essential component of the prereplication complex (pre-RC), which is recruited by the cdc6 and cdt1 proteins to origins of DNA replication during G(1) phase. Here, we report that the accumulation on chromatin of another member of the MCM protein family, human MCM8 (hMCM8)...

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Autors principals: Volkening, Melanie, Hoffmann, Ingrid
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC548026/
https://ncbi.nlm.nih.gov/pubmed/15684404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.4.1560-1568.2005
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