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Eliminating acetate formation improves citramalate production by metabolically engineered Escherichia coli
BACKGROUND: Citramalate, a chemical precursor to the industrially important methacrylic acid (MAA), can be synthesized using Escherichia coli overexpressing citramalate synthase (cimA gene). Deletion of gltA encoding citrate synthase and leuC encoding 3-isopropylmalate dehydratase were critical to a...
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| Publicado no: | Microb Cell Fact |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5480221/ https://ncbi.nlm.nih.gov/pubmed/28637476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-017-0729-2 |
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