Early pulmonary response is critical for extra-pulmonary carbon nanoparticle mediated effects: comparison of inhalation versus intra-arterial infusion exposures in mice

BACKGROUND: The death toll associated with inhaled ambient particulate matter (PM) is attributed mainly to cardio-vascular rather than pulmonary effects. However, it is unclear whether the key event for cardiovascular impairment is particle translocation from lung to circulation (direct effect) or i...

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Bibliografiske detaljer
Udgivet i:Part Fibre Toxicol
Main Authors: Ganguly, Koustav, Ettehadieh, Dariusch, Upadhyay, Swapna, Takenaka, Shinji, Adler, Thure, Karg, Erwin, Krombach, Fritz, Kreyling, Wolfgang G., Schulz, Holger, Schmid, Otmar, Stoeger, Tobias
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5480131/
https://ncbi.nlm.nih.gov/pubmed/28637465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12989-017-0200-x
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