Deducing in Vivo Toxicity of Combustion-Derived Nanoparticles from a Cell-Free Oxidative Potency Assay and Metabolic Activation of Organic Compounds

BACKGROUND: The inhalation of combustion-derived nanoparticles (CDNPs) is believed to cause an oxidative stress response, which in turn may lead to pulmonary or even systemic inflammation. OBJECTIVE AND METHODS: In this study we assessed whether the in vivo inflammatory response—which is generally r...

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Detalhes bibliográficos
Main Authors: Stoeger, Tobias, Takenaka, Shinji, Frankenberger, Birgit, Ritter, Baerbel, Karg, Erwin, Maier, Konrad, Schulz, Holger, Schmid, Otmar
Formato: Artigo
Idioma:Inglês
Publicado em: National Institute of Environmental Health Sciences 2009
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2627865/
https://ncbi.nlm.nih.gov/pubmed/19165387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.11370
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