Programmed death‐ligand 1 expression at tumor invasive front is associated with epithelial‐mesenchymal transition and poor prognosis in esophageal squamous cell carcinoma

Programmed death‐ligand 1 (PD‐L1) plays a crucial role in the host immune system in cancer progression. The gene promoter region of PD‐L1 also contains a binding site for ZEB1, a transcription factor related to epithelial‐mesenchymal transition (EMT). The purpose of this study was to clarify the rel...

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Publicat a:Cancer Sci
Autors principals: Tsutsumi, Satoshi, Saeki, Hiroshi, Nakashima, Yuichiro, Ito, Shuhei, Oki, Eiji, Morita, Masaru, Oda, Yoshinao, Okano, Shinji, Maehara, Yoshihiko
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5480087/
https://ncbi.nlm.nih.gov/pubmed/28294486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13237
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