Hemophilia as a defect of the tissue factor pathway of blood coagulation: effect of factors VIII and IX on factor X activation in a continuous-flow reactor.
The effect of factors VIII and IX on the ability of the tissue factor-factor VIIa complex to activate factor X was studied in a continuous-flow tubular enzyme reactor. Tissue factor immobilized in a phospholipid bilayer on the inner surface of the tube was exposed to a perfusate containing factors V...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1990
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54800/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2120704/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.19.7623 |
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