Hemophilia as a defect of the tissue factor pathway of blood coagulation: effect of factors VIII and IX on factor X activation in a continuous-flow reactor.

The effect of factors VIII and IX on the ability of the tissue factor-factor VIIa complex to activate factor X was studied in a continuous-flow tubular enzyme reactor. Tissue factor immobilized in a phospholipid bilayer on the inner surface of the tube was exposed to a perfusate containing factors V...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Repke, D, Gemmell, C H, Guha, A, Turitto, V T, Broze, G J, Nemerson, Y
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1990
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54800/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2120704/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.19.7623
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