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Impact of Chemical Analogs of 4-Hydroxybenzoic Acid on Coenzyme Q Biosynthesis: From Inhibition to Bypass of Coenzyme Q Deficiency

Coenzyme Q is a lipid that participates to important physiological functions. Coenzyme Q is synthesized in multiple steps from the precursor 4-hydroxybenzoic acid. Mutations in enzymes that participate to coenzyme Q biosynthesis result in primary coenzyme Q deficiency, a type of mitochondrial diseas...

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Библиографические подробности
Опубликовано в: :Front Physiol
Главный автор: Pierrel, Fabien
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5479927/
https://ncbi.nlm.nih.gov/pubmed/28690551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.00436
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