Epigenome-wide Analysis Links SMAD3 Methylation at Birth to Asthma in Children of Asthmatic Mothers

BACKGROUND: The timing and mechanisms of asthma inception remain imprecisely defined. Although epigenetic mechanisms likely contribute to asthma pathogenesis, little is known about their role in asthma inception. OBJECTIVE: To assess whether the trajectory to asthma begins already at birth and epige...

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Detaylı Bibliyografya
Yayımlandı:J Allergy Clin Immunol
Asıl Yazarlar: DeVries, Avery, Wlasiuk, Gabriela, Miller, Susan J., Bosco, Anthony, Stern, Debra A., Lohman, I. Carla, Rothers, Janet, Jones, Anya C., Nicodemus-Johnson, Jessie, Vasquez, Monica M., Curtin, John A., Simpson, Angela, Custovic, Adnan, Jackson, Daniel J., Gern, James E., Lemanske, Robert F., Guerra, Stefano, Wright, Anne L., Ober, Carole, Halonen, Marilyn, Vercelli, Donata
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5479765/
https://ncbi.nlm.nih.gov/pubmed/28011059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2016.10.041
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