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Intracellular delivery of biologic therapeutics by bacterial secretion systems
Biologics are a promising new class of drugs based on complex macromolecules such as proteins and nucleic acids. However, delivery of these macromolecules into the cytoplasm of target cells remains a significant challenge. Here we present one potential solution: bacterial nanomachines that have evol...
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| Veröffentlicht in: | Expert Rev Mol Med |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cambridge University Press
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5479498/ https://ncbi.nlm.nih.gov/pubmed/28382885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/erm.2017.7 |
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