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Intracellular delivery of biologic therapeutics by bacterial secretion systems

Biologics are a promising new class of drugs based on complex macromolecules such as proteins and nucleic acids. However, delivery of these macromolecules into the cytoplasm of target cells remains a significant challenge. Here we present one potential solution: bacterial nanomachines that have evol...

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Detalhes bibliográficos
Publicado no:Expert Rev Mol Med
Main Authors: Walker, Barnabas James, Stan, Guy-Bart V., Polizzi, Karen Marie
Formato: Artigo
Idioma:Inglês
Publicado em: Cambridge University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5479498/
https://ncbi.nlm.nih.gov/pubmed/28382885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/erm.2017.7
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