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YC-1 induces G(0)/G(1) phase arrest and mitochondria-dependent apoptosis in cisplatin-resistant human oral cancer CAR cells

Oral cancer is a serious and fatal disease. Cisplatin is the first line of chemotherapeutic agent for oral cancer therapy. However, the development of drug resistance and severe side effects cause tremendous problems clinically. In this study, we investigated the pharmacologic mechanisms of YC-1 on...

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Dettagli Bibliografici
Pubblicato in:Biomedicine (Taipei)
Autori principali: Lee, Miau-Rong, Lin, Chingju, Lu, Chi-Cheng, Kuo, Sheng-Chu, Tsao, Je-Wei, Juan, Yu-Ning, Chiu, Hong-Yi, Lee, Fang-Yu, Yang, Jai-Sing, Tsai, Fuu-Jen
Natura: Artigo
Lingua:Inglês
Pubblicazione: EDP Sciences 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5479426/
https://ncbi.nlm.nih.gov/pubmed/28612710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1051/bmdcn/2017070205
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