YC-1 induces G(0)/G(1) phase arrest and mitochondria-dependent apoptosis in cisplatin-resistant human oral cancer CAR cells

Oral cancer is a serious and fatal disease. Cisplatin is the first line of chemotherapeutic agent for oral cancer therapy. However, the development of drug resistance and severe side effects cause tremendous problems clinically. In this study, we investigated the pharmacologic mechanisms of YC-1 on...

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Detalles Bibliográficos
Publicado en:Biomedicine (Taipei)
Main Authors: Lee, Miau-Rong, Lin, Chingju, Lu, Chi-Cheng, Kuo, Sheng-Chu, Tsao, Je-Wei, Juan, Yu-Ning, Chiu, Hong-Yi, Lee, Fang-Yu, Yang, Jai-Sing, Tsai, Fuu-Jen
Formato: Artigo
Idioma:Inglês
Publicado: EDP Sciences 2017
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5479426/
https://ncbi.nlm.nih.gov/pubmed/28612710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1051/bmdcn/2017070205
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