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Effect of the sonic hedgehog receptor smoothened on the survival and function of dopaminergic neurons

OBJECTIVE: To determine the influence of the sonic hedgehog (shh) pathway and its receptor smoothened (smo), on the survival and functionality of dopaminergic (DA) neurons. BACKGROUND: During early development, shh induces the differentiation of DA neurons. However, it is unknown whether shh signali...

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Detalhes bibliográficos
Publicado no:Exp Neurol
Main Authors: Zhou, Xiaofei, Pace, Jonathan, Filichia, Emily, Lv, Tao, Davis, Brandon, Hoffer, Barry, Selman, Warren, Luo, Yu
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5479305/
https://ncbi.nlm.nih.gov/pubmed/27317298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2016.06.013
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