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Dopaminergic neuron-specific deletion of p53 gene is neuroprotective in an experimental Parkinson's disease model

p53, a stress response gene, is involved in diverse cell death pathways and its activation has been implicated in the pathogenesis of Parkinson's disease (PD). However, whether the neuronal p53 protein plays a direct role in regulating dopaminergic (DA) neuronal cell death is unknown. In this s...

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Bibliografiske detaljer
Udgivet i:J Neurochem
Main Authors: Qi, Xin, Davis, Brandon, Chiang, Yung-Hsiao, Filichia, Emily, Barnett, Austin, Greig, Nigel H., Hoffer, Barry, Luo, Yu
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5155515/
https://ncbi.nlm.nih.gov/pubmed/27317935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13706
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