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Dopaminergic neuron-specific deletion of p53 gene is neuroprotective in an experimental Parkinson's disease model

p53, a stress response gene, is involved in diverse cell death pathways and its activation has been implicated in the pathogenesis of Parkinson's disease (PD). However, whether the neuronal p53 protein plays a direct role in regulating dopaminergic (DA) neuronal cell death is unknown. In this s...

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Detalles Bibliográficos
Publicado en:J Neurochem
Autores principales: Qi, Xin, Davis, Brandon, Chiang, Yung-Hsiao, Filichia, Emily, Barnett, Austin, Greig, Nigel H., Hoffer, Barry, Luo, Yu
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5155515/
https://ncbi.nlm.nih.gov/pubmed/27317935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13706
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