Cryptotanshinone induces cell cycle arrest and apoptosis through the JAK2/STAT3 and PI3K/Akt/NFκB pathways in cholangiocarcinoma cells

BACKGROUND: Cholangiocarcinoma (CCA) is the most common biliary tract malignancy in the world with high resistance to current chemotherapies and extremely poor prognosis. The main objective of this study was to investigate the inhibitory effects of cryptotanshinone (CTS), a natural compound isolated...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Ke, Fayong, Wang, Zheng, Song, Xiaoling, Ma, Qiang, Hu, Yunping, Jiang, Lin, Zhang, Yijian, Liu, Yingbin, Zhang, Yong, Gong, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5479302/
https://ncbi.nlm.nih.gov/pubmed/28670110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S132488
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