Cryptotanshinone induces cell cycle arrest and apoptosis through the JAK2/STAT3 and PI3K/Akt/NFκB pathways in cholangiocarcinoma cells

BACKGROUND: Cholangiocarcinoma (CCA) is the most common biliary tract malignancy in the world with high resistance to current chemotherapies and extremely poor prognosis. The main objective of this study was to investigate the inhibitory effects of cryptotanshinone (CTS), a natural compound isolated...

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發表在:Drug Des Devel Ther
Main Authors: Ke, Fayong, Wang, Zheng, Song, Xiaoling, Ma, Qiang, Hu, Yunping, Jiang, Lin, Zhang, Yijian, Liu, Yingbin, Zhang, Yong, Gong, Wei
格式: Artigo
語言:Inglês
出版: Dove Medical Press 2017
主題:
Original Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5479302/
https://ncbi.nlm.nih.gov/pubmed/28670110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S132488
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