Bacillus anthracis Edema Toxin Increases Fractional Free Water and Sodium Reabsorption in an Isolated Perfused Rat Kidney Model

Bacillus anthracis edema toxin (ET) consists of protective antigen (PA), necessary for host cell toxin uptake, and edema factor (EF), the toxic moiety which increases host cell cyclic AMP (cAMP). Since vasopressin stimulates renal water and sodium reabsorption via increased tubular cell cAMP levels,...

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Vydáno v:Infect Immun
Hlavní autoři: Jaswal, Dharmvir S., Cui, Xizhong, Torabi-Parizi, Parizad, Ohanjanian, Lernik, Sampath-Kumar, Hannish, Fitz, Yvonne, Li, Yan, Xu, Wanying, Eichacker, Peter Q.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2017
Témata:
Bacterial Infections
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5478949/
https://ncbi.nlm.nih.gov/pubmed/28438974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00264-17
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