DNA methyltransferase 1 regulates reelin mRNA expression in mouse primary cortical cultures

The polygenic nature of complex psychiatric disorders suggests a common pathway that may be involved in the down-regulation of multiple genes through an epigenetic mechanism. To investigate the role of methylation in down-regulating the expression of mRNAs that may be associated with the schizophren...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Noh, Jai Sung, Sharma, Rajiv P., Veldic, Marin, Salvacion, Alain A., Jia, Xiaomei, Chen, Ying, Costa, Erminio, Guidotti, Alessandro, Grayson, Dennis R.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2005
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC547890/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15671176/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0409648102
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