Syk Plays a Critical Role in the Expression and Activation of IRAK1 in LPS-Treated Macrophages

To address how interleukin-1 receptor-associated kinase 1 (IRAK1) is controlled by other enzymes activated by toll-like receptor (TLR) 4, we investigated the possibility that spleen tyrosine kinase (Syk), a protein tyrosine kinase that is activated at an earlier stage during TLR4 activation, plays a...

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Pubblicato in:Mediators Inflamm
Autori principali: Park, Jae Gwang, Son, Young-Jin, Yoo, Byong Chul, Yang, Woo Seok, Kim, Ji Hye, Kim, Jong-Hoon, Cho, Jae Youl
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi 2017
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5478860/
https://ncbi.nlm.nih.gov/pubmed/28680194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/1506248
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