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Syk Plays a Critical Role in the Expression and Activation of IRAK1 in LPS-Treated Macrophages

To address how interleukin-1 receptor-associated kinase 1 (IRAK1) is controlled by other enzymes activated by toll-like receptor (TLR) 4, we investigated the possibility that spleen tyrosine kinase (Syk), a protein tyrosine kinase that is activated at an earlier stage during TLR4 activation, plays a...

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Detalles Bibliográficos
Main Authors: Jae Gwang Park, Young-Jin Son, Byong Chul Yoo, Woo Seok Yang, Ji Hye Kim, Jong-Hoon Kim, Jae Youl Cho
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Limited 2017-01-01
Series:Mediators of Inflammation
Acceso en liña:http://dx.doi.org/10.1155/2017/1506248
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