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Functional antagonism of different G protein-coupled receptor kinases for β-arrestin-mediated angiotensin II receptor signaling

β-arrestins bind to G protein-coupled receptor kinase (GRK)-phosphorylated seven transmembrane receptors, desensitizing their activation of G proteins, while concurrently mediating receptor endocytosis, and some aspects of receptor signaling. We have used RNA interference to assess the roles of the...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kim, Jihee, Ahn, Seungkirl, Ren, Xiu-Rong, Whalen, Erin J., Reiter, Eric, Wei, Huijun, Lefkowitz, Robert J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2005
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC547874/
https://ncbi.nlm.nih.gov/pubmed/15671181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409532102
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