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T-bet deficiency reduces atherosclerosis and alters plaque antigen-specific immune responses

The influence of the immune system on atherosclerosis involves both helper T (Th) cell and antibody responses to plaque antigens. These responses may have proatherogenic and protective effects. T-bet is a transcription factor required for Th1 differentiation and regulates the balance between Th1 and...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Buono, Chiara, Binder, Christoph J., Stavrakis, George, Witztum, Joseph L., Glimcher, Laurie H., Lichtman, Andrew H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC547865/
https://ncbi.nlm.nih.gov/pubmed/15665085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409015102
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